GTT (Glucose tolerance test)

GTT (Glucose tolerance test)

Definition: GTT mean Glucose tolerence test.It is a laboratory test to diagnose diabetic mellitus.

Indication:

  1. Mild DM.
  2. Almentary glycosuria.
  3. History of still birth,Spontaneous abortion.
  4. Premature labor,large baby.
  5. Hydramnios,toxaemia of pregnancy.

Importance:

  1. To find out the ability of the body to carbohydrate metabolism.
  2. To detect:DM,Endocrine dysfunction,Renal glycosuria.

Procedure/Method:

  1. Individual should be kept fasting for whole night(10-16 hours).
  2. Fasting venous blood for plasma and urine samples are collected.
  3. 75gm glucose in 250-300ml water is given by mouth.
  4. Venous blood and urine sample are collected either at the end of 2 hours or at half hourly intervals for 2-2.5 hours.
  5. Plasma glucose on each sample is estimated.Sugar or each urine sample is examined.

Result/Interpretation:

  1. Normal:Plasma/serum glucose value in all samples are with in normal range there is no sugar in urine.
  2. Diabetes:
Normal DM
Fasting Less than 5.5 7.8 or more
2 hours after 75gmglucose Less than 7.8 11.1 or more
  1. Impaired glucose tolerence: Intermediated between normal and Diabetes.
  • Fasting glucose 5.5-7.8 mmol/L
  • Post prandial glucose 7.8-11.1 mmol/L
  1. Renal glycosuria: Blood glucose values are normal but suger is present in urine due to renal threshold value for glucose.

 

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