complete blood count (CBC)

complete blood count (CBC)

complete blood count (CBC), also known as a complete blood cell countfull blood count (FBC), or full blood exam(FBE), is a blood panel  requested by a doctor or other medical professional   that gives information about the cells in a patient’s blood. A scientist or lab technician performs the requested testing and provides the requesting medical professional with the results of the CBC.

Blood counts of various types have been used for clinical purposes since the 19th century. Automated equipment to carry out complete blood counts was developed in the 1950s and 1960s.

The cells  that circulate in the bloodstream  are generally divided into three types: white blood cells (leukocytes ), red blood cells ( erythrocytes), and platelets (thrombocytes). Abnormally high or low counts may indicate the presence of many forms of disease, and hence blood counts are amongst the most commonly performed blood tests  in medicine, as they can provide an overview of a patient’s general health status. A CBC is routinely performed during annual physical examinations in some jurisdictions

Results

An example report format for a complete blood count. Note that test names, measurement units and reference ranges may vary between countries and laboratories. Patient results should always be interpreted using the units and reference ranges from the laboratory that produced the results.

Interpretation

Certain disease  states are defined by an absolute increase or decrease in the number of a particular type of cell in the bloodstream.

complete-blood-count

For example:

Type of Cell Increase Decrease
 Red Blood Cells(RBC) erythrocytosis or polycythemia anemia or erythroblastopenia
 White Blood Cells (WBC): leukocytosis leukopenia
 Lymphocytes lymphocytosis – lymphocytopenia
 Granulocytes granulocytosis  granulocytopenia or agranulocytosis
Neutrophils neutrophilia – –neutropenia
Eosinophils eosinophilia – –eosinopenia
Basophils basophilia – –basopenia
Platelets  thrombocytosis thrombocytopenia
All cell lines pancytopenia

Many disease states are heralded by changes in the blood count:

  •  Leukocytosis can be a sign of infection
  •  Thrombocytopenia can result from drug toxicity
  •  Pancytopenia is generally referred to as the result of decreased production from the bone marrow,   and is a common complication of cancer chemotherapy.

 

 

 

 

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