Syllabus (Biochemistry)

Biochemistry

Total Lecture: 100 Hrs

Exam Time: 3 Hrs.

  Total marks: 150

Written: 100

                                                                    Oral / Practical: 30

                                                                                                                        Sessional: 20

Biophysics: Concepts of pH and buffers, acid base equilibrium osmotic Pressure and its physiological applications.

Cell: morphology, structure & kinetics of cell, membrane, Nucleus, chromatin, Mitochondria, Endoplasmic Reticulum, Ribosomes.

Carbohydrates: Definition, functions, sources, classifications, Monosaccharide, Disaccharides, Polysaccharides, mucopolysaccharide and its importance,

Lipids: Definition, function, sources, classification, simple lipid, compound lipid, derived lipid, unsaturated and saturated fatty acid, Essential fatty acids and their importance, Blood lipids and their implications, cholesterol and its importance,

Proteins: Definition, sources, kinetics, classification, simple protein, conjugated protein, derived proteins, properties and varieties and varieties of proteins.

Nucleic acid: Structure and function of DNA and RNA, Nucleosides, nucleotides, Genetic code, biologically important nucleotides.

Enzymes: Definitions, classification, mode of action, factor affecting enzyme action, clinical importance of enzyme.

Vitamins: Classification, fat-soluble vitamins, A, D, E & K, water-soluble vit-B complex & c, Daily Requirements, Physiological functions and deceases of Vitamin deficiency.

Bioenergetics: Concept of free energy change,  Exogenic and endogenic reactions, concepts regarding energy rich compounds, Respiratory chain and Biological oxidation.

Carbohydrate Metabolism: Glycolysis, HMP shunt pathway, TCA cycle,  glycogenesis, glycogenolysis, Glucogenesis,  Maintenance of Blood Glucose. interconversions of different sugar.

Lipid Metabolism: Fatty acid oxidation, Fatty acid synthesis, Metabolism of cholesterol, Ketone bodies, Atherosclerosis and obesity.

Protein Metabolism: Transamination, Transmethylation, Deamination, Fate of ammonia urea synthesis and synthesis of cretonne, inborn errors of metabolism.

Water and Electrolyte: Fluid compartment, daily intake and output sodium and potassium metabolism.

Nutrition: Balance diet, metabolism in exercise and injury, Diet for chronically ill and terminally ill patients.

Connective tissue: Mucopolysaccharide connective tissue proteins glycoproteins, chemistry & Metabolism of bone and tooth metabolism of skin.

Nerve tissue: Composition, metabolism chemical mediators of nerve activity.

Hormones: General characteristics and mechanism of Hormone action insulin, glucagone Thyroid and Parathyroid hormones, cortical & sex hormones.

Isotopes: Isotopes and their role in treatment and diagnosis of diseases.

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