UNIVERSITY OF DHAKA
3rd Professional B.Sc in Physiotherapy Examination November 2010
Subject: Pharmacology-I (New Curriculum)
Full marks: 100 Time: 3hours
Use separate answer script for each group
Answer any three (03) parts from each question
All questions carry equal marks
Q.No:01:a)What is drug?Enumerate the sources of drug with example.
b)Define Bioavailability.What are the significance of bioavailability study?What are the factors modifying bioavailability?
c)Describe the factors modifying drug action.
d)Write short notes: i)Prodrug ii)Hepatic first pass metabolism
Q.No:02:a)Enumerate the routes of administration of drugs.What are the advantages of intervenous route and disadvantages of intramuscular route.
b)Define Biotrasformation.What are the sites of biotrasformation with wxamples?What are the aims and objectives of biotransformation?
c)Name the routes of drug excretion with examples.What are the factors that modifying drug excretion through kidney?
d)Write short notes: i)Plasma half life ii)Therapeutic index
Q.NO:03:a)Define and classify antibiotics.
b)What are the tetracyclines and why they are called so?Enumerate its adverse effects.
c)Give the regimen of anti tubercular therapy.Write down the important adverse effects of antitubercular drugs.
d)Write short notes: i)Receptor mechanism of drug action ii)Grey baby syndrome
Q.No:04:a)Classify Cephalosporin.Write down the indication and adverse effects of Cephalosporin.
b)Write down the drugs used in the teatment of petic ulcer disease(PUD).Justify the use of H2 blocker in the management of PUD.
c)Classify NASIDs.What are the indicatoins of Aspirin?
d)Write short notes: i)Anti-diabetic drugs ii)Antifungal drugs