UNIVERSITY OF DHAKA
2nd Professional B.Sc in Physiotherapy Examination February 2010
Subject: Pathology & Microbiology-I (New Curriculum)
Full marks: 100 Time: 3hours
Use separate answer script for each group
Answer any two parts from each question
All questions carry equal marks
Q: No: 01: a) What are the causes of cell injury? Discuss the mechanism of hypoxic cell injury.
b) Name the chemical mediators of inflammation. Write about their source and function.
c) Describe the pathogenesis and laboratory diagnosis of poliomyelitis. How can you immunize a child against polio virus?
Q: No: 02: a) What are the factors influencing wound healing? What are the complicaitons of wound healing?
b) Define cellular adaptation. What are the adaptive changes? Describe about metaplasia.
c) Define necrosis and apoptosis. What are the types of necrosis? Give example. What are the difference between necrosis and apoptosis?
Q: No: 03: a) Discuss the generation of arachidonic acid metabolites and their role in inflammation. What are the fates of acute inflammation?
b) Describe the pathogenesis and laboratory diagnosis of enteric fever.
c) Write short notes on: i) Difference between exotoxin and endotoxin of bacteria ii) Dystrophic calcification iii) Mantoux test iv) Granulation tissue
Q: No: 04: a) Define oedema. Name the conditions that lead to generalized oedema. Write down the patahophysiologic categories of oedema.
b) What is metasis? Name the routes of metasis. State the mechanism of invasion & metastasis of malignant tumor.
c) Define and classify anaemia. What are the causes of microcytic hypocromic anaemia.
Q: No: 05: a) Define and classify vitamins. What are the sources of vitamin-A. Discuss about deficiency manifestations of vitamin-A.
b) Give the aetiopathogenesis of rheumatic fever. How a case of rheumatic fever is diagnosed? What are the major and minor criteria for diagnosis of rheumatic fever
c) What is shock? What are the types of shock? Discuss the pathogenesis of septic shock.
Q: No: 06: a) What is tumor marker? Name the tumor markers with associated cancers. Discuss in short about the value of tumor markers in diagnosis and management of cancer patient.
b) Name the causative agents of tuberculosis. Write down the laboratory diagnosis of TB.
c) Write short notes (any three): i) Difference between exudate and transudate ii) Oncogenic viruses iii) Myopathies iv) Rheumatoid arthritis